Cross-source consensus on what matters today in genetics and genomics — drawn from 16 trusted public sources including NHGRI, the CDC, NHS England, Genomics England, the PHG Foundation, the Wellcome Sanger Institute, and peer-reviewed open-access journals.
Last updated: · browse archive
Aurora Therapeutics, which aimed to industrialise bespoke CRISPR gene-editing treatments modelled on the Baby KJ case, has abandoned its programme, citing regulatory demands that a small company could not meet.
A new study proposes that the intense transcriptional activity of cancer superenhancers inflicts recurrent DNA double-strand breaks, with imperfect repair generating the mutations that fuel tumour evolution.
A preprint integrating DNA methylation data across 20 solid cancers finds that epigenetic age acceleration is not uniform — some tumour types appear younger than matched normal tissue, others older.
Genomic analysis has identified signatures of introgression from two distinct extinct human populations beyond the Neanderthal and Denisovan contributions already known from ancient DNA research.
A preprint using CITE-seq data from over one million peripheral blood mononuclear cells pinpoints the causal allele at the CD40 locus and maps downstream trans-acting effects specific to activated B cells, pointing toward targeted rather than broadly immunosuppressive therapies.
A study reports that blood cancers destined to worsen carry identifiable genomic changes long before clinical progression, potentially helping researchers distinguish pathological from age-related haematopoietic changes.
An analysis of more than three million Wikipedia revisions across nearly 7,000 pages finds genetics terminology is disproportionately concentrated in articles about nationality and ethnicity, raising questions about how research on human genetic diversity is synthesised for public audiences.
A major genome-wide study has expanded the known genetic architecture of hyperemesis gravidarum to ten risk genes, several of which implicate appetite and nausea regulation pathways.
A bioRxiv preprint identifies a transient window of extreme TCOF1 dosage-sensitivity in cranial neural crest cells, offering a mechanistic explanation for the tissue-specific effects of Treacher Collins syndrome.
Reports of a death in a gene-editing clinical trial in China have raised fresh questions about trial design, informed consent, and international oversight of human genome-editing research.
About Genetic Current
Genetic Current is the news section of Evagene, an academic, research, and educational pedigree-modelling platform. Stories are AI-drafted summaries of items from trusted public sources, written for researchers, clinicians, educators, students, genealogists, and patients with an interest in genetics. Summaries are for educational and research purposes only and are not medical advice.
Join the Evagene Alpha Waiting List