Nature Genetics publishes author correction to RNU4-2 neurodevelopmental syndrome paper

Nature Genetics has published an author correction to a previously reported paper describing biallelic variants in the noncoding RNA gene RNU4-2 as the cause of a recessive neurodevelopmental syndrome characterised by distinct white matter changes on neuroimaging.

The original study was a significant finding in the rare neurodevelopmental disease field, identifying pathogenic variants in a small nuclear RNA gene — a class of gene not previously well-established as a cause of Mendelian disease. Author corrections in peer-reviewed journals may address errors in data presentation, figures, supplementary materials, or author attribution; the specific nature of this correction is not detailed in the feed entry.

Readers following this research area — particularly those in clinical genetics, rare disease research, and genetic counselling for families affected by unexplained neurodevelopmental conditions — should note the correction and consult the updated article directly via Nature Genetics. The correction does not necessarily affect the principal findings of the original work; readers should review the correction notice for detail.