PLOS Genetics issues correction to meta-evolutionary exome study of type 2 diabetes genes

PLOS Genetics has published a correction to the paper 'Meta-evolutionary exome analysis identifies novel type 2 diabetes mellitus genes in the UK Biobank and All of Us', as announced by the PLOS Genetics editorial staff. The original paper applied a meta-evolutionary analytical framework to whole-exome sequencing data from two large biobank cohorts — the UK Biobank and the National Institutes of Health All of Us Research Programme — to identify candidate genes for type 2 diabetes mellitus.

The lede provided with the correction notice contains no detail on the nature or extent of the changes made. Readers who have cited or built upon the original paper are advised to review the correction notice directly via the PLOS Genetics article page to determine whether any results or conclusions are affected.

Genetic Current will monitor for any further editorial notices associated with this paper. Corrections to large GWAS and exome studies are not uncommon and do not necessarily indicate fundamental problems with the original findings, but the specific scope of this correction is not yet clear from the available information.