Getting started

Evagene user guide

A click-by-click tour of the Evagene editor, organised around the floating dock. Every section below has its own page with a worked example you can follow on your own pedigree. This guide assumes you understand the genetics; it does not assume you have used Evagene before.

The Evagene editor showing an example family pedigree on the canvas with the floating dock toolbar.
The Evagene editor: an example pedigree on the canvas, with the floating dock. Example family; outputs are illustrative.

The three things on screen

Open a pedigree and you are looking at three elements. Understand these and everything else follows.

1. The canvas

The drawing surface. You add individuals, connect them into families, and select them here.

2. The dock

The floating toolbar. Its buttons are grouped: edit, view, file, structure, and the clinical & genetics catalogues. Drag the grip to reposition it.

3. The panels

Floating windows opened from the dock. Every panel is draggable and resizable from any edge or corner, and its dock icon highlights while it is open.

Tour of the dock

The dock reads left to right in groups. Each group maps to a page in this guide.

Canvas basics — edit & context actions

Undo · Redo · Find · Add · Marry · Siblings · Parents · Delete

Add your first individual, select people, connect them into a family, undo mistakes, and find anyone by name.

View & layout

Grid · Zoom · Font · Dark mode · Auto-arrange

Snap to a grid, zoom, set the label font, switch to dark mode, and auto-arrange a tangled tree.

Pedigree builder

Drag-and-drop family construction

Build a family quickly with relationship-aware shortcuts: spouse, children, siblings, parents, grandparents, twins.

Individual properties

Identity · Clinical · Dates · Contact · Consent

The main editing panel for a person: names, biological sex, mortality and affection status, dates, and more.

Pedigree & relationship properties

Pedigree-level settings · Consanguinity · Events

Name the pedigree, toggle consanguinity coefficients, and edit a couple's relationship and events.

Family register (grid view)

Sortable table · Bulk edits · Visibility

A spreadsheet view of everyone in the pedigree for fast edits, sorting, and showing or hiding branches.

Files — import, export & 23andMe

Evagene · GEDCOM · XEG · Image · PDF/DOCX · 23andMe

Load and save pedigrees, export images and documents, and import 23andMe data. Includes the CanRisk / BOADICEA bridge.

Disease catalogue

230+ diseases · Assign to individuals

Add diseases to your pedigree's working set, then assign them to individuals with affection status and manifestations.

Investigations Manager (formerly Tests Manager)

Clinical test types · Results

Record clinical investigations with reference ranges, LOINC codes, and results on individuals.

Interventions

Treatments · Dose · Status · Prophylactic

Track treatments and interventions on an individual: dose, frequency, dates, and disease association.

Genetics — markers, karyogram, karyotype, ancestry

Blade navigation · Genome drill-down

Define markers, record genotypes, view the karyogram, set a karyotype, and record ancestry proportions.

Related concepts

Educational correlation graph

Explore educational associations between recorded concepts. Reference data — not risk analysis or diagnosis.

Risk analysis

20 models · Illustrative / educational

Run the published risk models on your pedigree for teaching and research. Outputs are illustrative, not clinical recommendations.

A suggested first session

If this is your first time, work through these five pages in order. Twenty minutes end to end, and you will have built, annotated, and explored a small family.

  1. 1
    Canvas basics — draw your first three individuals and connect them.
  2. 2
    Individual properties — fill in names, sex, and dates.
  3. 3
    Disease catalogue — add a disease and mark an affected relative.
  4. 4
    Risk analysis — set a proband and run one model.
  5. 5
    Export — save your work and export an image.

About Evagene. Evagene is an academic, research, and educational pedigree modelling platform. It is not a medical device and is not intended to diagnose, prevent, monitor, predict, treat, or manage disease, or to determine eligibility for screening, testing, referral, or treatment, or to replace professional clinical judgement. Outputs are illustrative and for educational / research purposes only.

Try it on your own pedigree

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